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Wet table salt and its saturated hypertonic solution for treating retinoic acid resistant plane viral warts on face
Address for correspondence: Dr. Muhammed Mukhtar, Mukhtar Skin Centre, Katihar Medical College Road, Katihar-854105, India. E-mail: drmmukhtar20@gmail.com
This article was originally published by Wolters Kluwer - Medknow and was migrated to Scientific Scholar after the change of Publisher.
Abstract
Abstract
Plane viral warts on the face can be difficult to treat at times. Various treatment approaches for facial viral warts have had variable degrees of effectiveness. In contrast, the majority of existing treatments are more costly, painful, and difficult to manage. In approximately 15.6% of instances, retinoic acid (0.05%) is also ineffective. It is very difficult to cure warts on the face at a young age. In pyogenic granuloma, table salt (NaCl) is useful as a sclerosing agent, and its hypertonic solution (15%) is effective in prolabial mucoceles. The aim of treating viral warts is to necrose infected cells and sclerose or thrombose their feeding capillaries at the wart’s base.
Keywords
Face
hypertonic solution
keratolytic agent
plane viral wart
retinoic acid
table salt
CHALLENGE
A number of times, plane viral warts on the face present a therapeutic challenge. Various treatment modalities for plane viral warts on the face have shown varying degrees of success.[1] The majority of available therapies, on the other hand, are more expensive, painful, and difficult to obtain. Retinoic acid (0.05 percent) is also not effective approximately in 15.6% of cases.[2] Furthermore, treating warts on the face at a young age is difficult. Table salt (NaCl) is effective as a sclerosing agent in pyogenic granuloma,[3] and its hypertonic solution (15%) in prolabial mucoceles.[4] The goal of treating viral warts is to necrosis the infected cells and sclerose or thrombose their feeding capillaries, which are located at the base of the wart. However, using a saturated hypertonic solution of table salt as a topical sclerosing agent on intact hyperkeratotic plane warts is difficult.
SOLUTION
We selected the cases of retinoic acid resistant plane viral warts in the age group 9 to 15 years. For treating the warts, a pinch of table salt is wrapped in gauze and dipped in warm tap water before being applied to the warts two to three times per day for 3 to 5 minutes, and retinoic acid (0.05%) in the night. To make the procedure simple, a saturated hypertonic saline of table salt (SHSTS) of 35.9 percent is made and used in place of wet table salt by dissolving 40 to 50 grams of salt in 100 ml of tap water. The solution’s concentration is approximately 40 times that of normal isotonic saline. For six weeks, the procedure is repeated every day. The patients are followed up weekly. The warts resolved in 3 to 4 weeks. The treated sites had dryness, itching, and hyperpigmentation for the short term. SHSTS’s mechanism of action is not well known, but it has disinfectant, exfoliative, and osmotic properties, as well as the ability to increase apoptosis, immune modulation, and reduce post-injury inflammation. As a result, combining warm wet table salt or its SHSTS with retinoic acid could be an effective treatment option for chronic viral warts on the face [Figure 1a–c]. In this resistant case, retinoic acid is used as a keratolytic agent to improve the penetration and effectiveness of the salt or its solution. Instead of retinoic acid or other keratolytic agents, few warts can be pinched out with the tip of a small mosquito forceps [Figure 2a–c]. This method was used to treat three patients who had warts on their faces. However, it is a preliminary report. The effectiveness of the salt with or without retinoic acid as a cost-effective, readily available therapy should be studied in a large number of patients in a controlled clinical study.
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflict of interest
There are no conflicts of interest.
Acknowledgment
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