Journal of Cutaneous and Aesthetic Surgery
Print this page
Email this page
Small font size
Default font size
Increase font size
Home About us Current issue Archives Instructions Submission Subscribe Editorial Board Partners Contact e-Alerts Login 
Year : 2022  |  Volume : 15  |  Issue : 1  |  Page : 71-76

A comparative study of efficacy of 5% minoxidil and 5% minoxidil plus platelet-rich plasma in same patient for treatment of androgenetic alopecia

Department of Dermatology, Venereology, and Leprosy, Dr S. N. Medical College, Jodhpur, Rajasthan, India

Correspondence Address:
Dr. Dilip Kachhawa
Bunglow No. 3 O/s MDM Hospital, Jodhpur, Rajasthan 342003
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JCAS.JCAS_232_20

Rights and Permissions

Background: Androgenetic alopecia (AGA) is characterized by androgen-related progressive thinning of the scalp hair in a defined pattern. It has an effect on social and psychological well-being of the patient. It is often recalcitrant to medical treatment alone. Aim: The aim of the study was to compare the efficacy of 5% minoxidil and 5% minoxidil plus platelet-rich plasma (PRP) in same patient for the treatment of AGA. Materials and Methods: A prospective randomized study was conducted on 50 patients of AGA attending the outdoor department. Scalp of each patient was divided into right side and left side, to compare the effectiveness of 5% minoxidil on the right side with combination of 5% minoxidil and intradermal PRP on the left side at an interval of 1 month for a period of 6 months. Clinical improvement was assessed monthly till 6 months by the serial hair pull test, global photography, patient satisfaction score, trichoscopic evaluation, and hair density. Results: For post-procedure subjective perception at the end of 6 months, the minoxidil 5% side showed good response in 41% (n = 18), moderate in 20% (n = 9), and poor in 39% (n = 17), whereas the PRP + minoxidil 5% side showed good response in 59% (n = 26), moderate in 16% (n = 7), and poor in 25% (n = 11) of the patients. Conclusion: The combination consists of 5% minoxidil and intradermal PRP, which appears to be simple, safe, and effective treatment in AGA. It can be used in poor responders in conventional medical therapy.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded123    
    Comments [Add]    

Recommend this journal