Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors
Search in posts
Search in pages
Filter by Categories
Authors’ Reply
BRIDGING THE GAP
BRIEF COMMUNICATION
BRIEF REPORT
Case Report
Case Reports
Case Series
CME
CME ARTICLE
CME articles - Practice points
COMMENTARY
CONFERENCE REPORT
CONTROVERSY
Correspondence
Correspondences
CUTANEOUS PATHOLOGY
DRUG REVIEW
E-CHAT
Editorial
EDITORIAL COMMENTARY
ERRATUM
ETHICAL HOTLINE
ETHICS
Field: Evolution of dermatologic surgergy
FOCUS
FROM THE ARCHIVES OF INDIAN JOURNAL OF DERMATO SURGERY
From the Editor's Desk
FROM THE LITERATURE
GUEST EDITORIAL
Guidelines
Images in Clinical Practice
Images in Dermatosurgery
INNOVATION
Innovations
INVITED COMMENTARY
JCAS Symposium
LETTER
Letter to Editor
Letter to the Editor
LETTERS
Message from the President
NEW HORIZON
Original Article
Practice Point
Practice Points
PRESIDENTIAL SPEECH
QUIZ
RESEARCH ARTICLE
Resident’s Page
Review
Review Article
Review Articles
SHORT COMMUNICATION
Spot the Diagnosis [Quiz]
STUDY
SURGICAL PEARL
SYMPOSIUM
Symposium—Lasers
Symposium: Hair in Dermatology
Symposium: Lasers Review Article
View Point
VIEWPOINT
VIEWPOINTS
Generic selectors
Exact matches only
Search in title
Search in content
Post Type Selectors
Search in posts
Search in pages
Filter by Categories
Authors’ Reply
BRIDGING THE GAP
BRIEF COMMUNICATION
BRIEF REPORT
Case Report
Case Reports
Case Series
CME
CME ARTICLE
CME articles - Practice points
COMMENTARY
CONFERENCE REPORT
CONTROVERSY
Correspondence
Correspondences
CUTANEOUS PATHOLOGY
DRUG REVIEW
E-CHAT
Editorial
EDITORIAL COMMENTARY
ERRATUM
ETHICAL HOTLINE
ETHICS
Field: Evolution of dermatologic surgergy
FOCUS
FROM THE ARCHIVES OF INDIAN JOURNAL OF DERMATO SURGERY
From the Editor's Desk
FROM THE LITERATURE
GUEST EDITORIAL
Guidelines
Images in Clinical Practice
Images in Dermatosurgery
INNOVATION
Innovations
INVITED COMMENTARY
JCAS Symposium
LETTER
Letter to Editor
Letter to the Editor
LETTERS
Message from the President
NEW HORIZON
Original Article
Practice Point
Practice Points
PRESIDENTIAL SPEECH
QUIZ
RESEARCH ARTICLE
Resident’s Page
Review
Review Article
Review Articles
SHORT COMMUNICATION
Spot the Diagnosis [Quiz]
STUDY
SURGICAL PEARL
SYMPOSIUM
Symposium—Lasers
Symposium: Hair in Dermatology
Symposium: Lasers Review Article
View Point
VIEWPOINT
VIEWPOINTS
View/Download PDF

Translate this page into:

Innovations
16 (
2
); 147-148
doi:
10.4103/JCAS.JCAS_88_22

Sealing of Follicular Openings in Keloid with Cyanoacrylate Glue for Effective Intralesional Therapy

Department of Dermatology, Mukhtar Skin Centre, Katihar, Bihar, India

Address for correspondence: Dr. Muhammed Mukhtar, Mukhtar Skin Centre, Katihar Medical College Road, Katihar 854105, Bihar, India. E-mail: drmmukhtar20@gmail.com

Licence
This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Disclaimer:
This article was originally published by Wolters Kluwer - Medknow and was migrated to Scientific Scholar after the change of Publisher.

Abstract

Abstract

Intralesional therapy is a common treatment for keloid. However, because of some follicular openings and comedones on the surface of the keloid on the hairy chest and acne keloidalis, there is a risk of drug leakage, and sometimes ejection of drugs like a jet spray leads to therapy being ineffective. The authors describe a novel and effective method for preventing drug loss from follicular openings during intralesional therapy. To prevent drug loss during intralesional injection, cyanoacrylate glue is applied to the follicular and comedone openings on the keloid’s surface.

Keywords

Cyanoacrylate glue
follicular openings
hemostasis
intralesional therapy
jet spray
keloids
leakage
sealing

CHALLENGE

In dermatology, intralesional injection therapy is a common treatment for keloid.[12] However, because of some follicular openings and comedones on the surface of the keloid on the hairy chest and acne keloidalis, there is a risk of drug leakage, and sometimes ejection of drugs like a jet spray leads to therapy being ineffective. The authors describe a novel and effective method for preventing drug loss from follicular openings during intralesional therapy.

SOLUTION

To prevent drug loss during intralesional injection, cyanoacrylate glue is applied to the follicular and comedone openings on the keloid’s surface [Figure 1]. After 3–5 min, the glue cures, hardens, and seals the openings. Following that, the injection is given into the keloid tissue with a Leur lock syringe without any drug leakage from the follicular opening. For the bleeding at the injection sites after the injection therapy, hemostasis is achieved with cyanoacrylate glue [Figure 2]. Thus, cyanoacrylate glue is a novel and effective use for effective intralesional therapy of keloid with hemostasis. Cyanoacrylate is a nonirritant, nonallergenic US Food and Drug Administration (FDA) proven adhesive glue having antibacterial, antiseptic, dehydrating (moisture absorber due to exothermic heat production), and sealing properties. In general, the glue remains on the skin for 4–5 days. Usually within a week, it gets dislodged from the follicular openings and skin surface without much effort during taking a bath. There is no incidence of secondary bacterial infection or any adverse effects of the glue seen at the sites. If necessary, the glue can be dissolved or easily removed using an acetone solution.

Intralesional injection is given after sealing of follicular openings and comedones on the surface of keloid with cyanoacrylate glue
Figure 1
Intralesional injection is given after sealing of follicular openings and comedones on the surface of keloid with cyanoacrylate glue
The post bleeding from injection pricks that are sealed with the glue
Figure 2
The post bleeding from injection pricks that are sealed with the glue

Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.

REFERENCES

  1. , , . Intralesional drug therapy in dermatology. Indian J Dermatol Venereol Leprol. 2017;83:127-32.
    [Google Scholar]
  2. , , , , , . Creating a guard with a needle cover to control the depth of intralesional injections. J Am Acad Dermatol. 2016;75:e67-8.
    [Google Scholar]
Show Sections